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[3 + 2] Cycloaddition and Cascade Radical Reactions for the Synthesis of Trifluoromethylated Tetrahydrobenzodiazepin-3-ones

Muthengi, Alex; Erickson, Jon; Muriph, Rachel E.; Zhang, Wei (2019-04-01)

A reaction sequence involving three-component [3 + 2] cycloaddition of azomethine ylides followed by CuI catalyzed cascade trifluoromethyl radical addition and cyclization is developed for diastereoselective synthesis of ...

[3+2] Cycloaddition-based one-pot synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold

Zhang, Xiaofeng; Legris, Marc; Muthengi, Alex; Zhang, Wei (2017-01)

Three-component [3+2] cycloaddition followed by reduction and lactamization has been developed as a one-pot methodology for diastereoselective synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold.

Access to Information, Personal and Social Needs as Learner Support Services in Open, Distance and E-Learning Programme in Selected Public Universities in Kenya

Mutabari, Laichena; Ireri, Irene W. (2020)

Rapid technological changes in education have become paramount towards meeting educational demands. The use of Information Communication Technology (ICT) has helped in bringing down the traditional barriers of access of ...