Department of Basic Sciences: Recent submissions
Now showing items 21-40 of 41
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Optimization of Glycerol Production from Mango Seed Oil Using Response Surface Methodology and Central Composite Design
(2023-10)The objective of this research was to optimize the glycerol production from mango seed oil using RSM and CCD. The glycerol was produced through the transesterification process where biodiesel and glycerol were produced as ... -
Optimization Of Oil Production From Mango Seed Using Response Surface Methodology And Central Composite Design
(2023-10)Response Surface Methodology (RSM) and Central Composite Design (CCD) is an important statistical tool for modeling and analysis of statistical problems where the response of interest is influenced by several variables ... -
Modeling Covariates of Infant and Child Mortality in Kenya
(2020-08)Mortality of children under the age of five has been target of public health policies. There has been a significant decline in under-five mortality in the twenty first century in almost all countries several studies have ... -
Adsorption of Lead (II) Ions from Aqueous Solutions Using Mangroves Roots (Rhizophora Mucronata) Charcoal-Carbon Nanotubes Nanocomposite
(2021-02)Providing clean and affordable water to meet human needs is a grand challenge of the 21st century. Worldwide, water supply struggles to keep up with the fast growing demand, which is exacerbated by population growth, global ... -
Adsorption of rhodamine b from aqueous solution using mangroves (Rhizophora mucronata) carbon nanotubes nanocomposites
(2021-03-03)The use of dyes has increased dramatically and uncontrollably in last few decades. Different types of dyes are frequently employed in plastics, paper, cosmetics, leather, and textile industries for coloring purposes. These ... -
A review on chemistry of some species of genus Vepris (Rutaceae family)
(2014)This review presents the current known phytochemical constituents of the genus Vepris. The genus is a rich source of alkaloids and limonoids most of which possess the 3, 4-methylenedioxy moieties. They are frequently used ... -
Chemical Constituents in Extracts from Leaves of Lantana trifolia and Their In Vitro Anti-oxidative Activity
(2014)Objective To isolate, purify, and analyze the anti-oxidants from the leaves of Lantana trifolia. Methods The anti-oxidative activities of the crude extracts from liquid-liquid extraction of L. trifolia leaves were assayed ... -
Isolation and Identification of Bioactive Constituents from Stem Barks of Illicium difengpi
(2014)Objective To isolate and identify bioactive constituents from the stem barks of Illicium difengpi. Methods The chemical constituents were isolated and purified by repeated silica gel, Sephadex LH-20, recrystallization, and ... -
A review on toxicity effects on Aconitum carmichaelii Debx (Chuan wu and Fuzi) and TCM processing approach ‘Pao zhi’ in reducing/ eliminating toxicity
(2015)Aconitum carmichaelii Debx. (Chuan wu & Fuzi) is one of the most widely used Chinese traditional medicinal herbs and is listed in the Chinese Pharmacopoeia. It has been used for the treatment of various conditions rheumatism ... -
A review on phenolic compounds in Illicium species and their pharmacological effects
(2013)This review focuses mainly on findings of chemistry and pharmacological activities of phenolic compounds in Illicium plants. The continued chemical studies of Illicium species such as I.difengpi, I.verum, I.griffithii, ... -
Proximate Composition, Mineral Element Profile and Antioxidant Properties of the Edible Kenyan Mushroom, Auricularia polytricha
(2022-07)The indigenous Kenyan Auricularia polytricha is a known delicacy to the communities residing around Kakamega forest in Western Kenya. The objective of the present study was to carry out proximate analysis, determine ... -
Stereoselective synthesis of fused tetrahydroquinazolines through one-pot double [3 + 2] dipolar cycloadditions followed by [5 + 1] annulation
(2016-10)The one-pot [3 + 2] cycloaddition of an azomethine ylide with a maleimide followed by another [3 + 2] cycloaddition of an azide with the second maleimide gives a 1,5-diamino intermediate which is used for a sequential ... -
[3+2] Cycloaddition-based one-pot synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold
(2017-01)Three-component [3+2] cycloaddition followed by reduction and lactamization has been developed as a one-pot methodology for diastereoselective synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold. -
One-pot and catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates†
(2017)A method for the catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates is develo ped through a one-pot synthesis involving denitrogenation of azide, benzisoxazole formation, aza-Diels– Alder ... -
Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors
(2018)The simultaneous inhibition of polo-like kinase 1 (PLK1) and BRD4 bromodomain by a single molecule could lead to the development of an effective therapeutic strategy for a variety of diseases in which PLK1 and BRD4 are ... -
[3 + 2] Cycloaddition and Cascade Radical Reactions for the Synthesis of Trifluoromethylated Tetrahydrobenzodiazepin-3-ones
(2019-04-01)A reaction sequence involving three-component [3 + 2] cycloaddition of azomethine ylides followed by CuI catalyzed cascade trifluoromethyl radical addition and cyclization is developed for diastereoselective synthesis of ... -
Development of Dimethylisoxazole-Attached Imidazo[1,2‑a]pyridines as Potent and Selective CBP/P300 Inhibitors
(2021)The use of epigenetic bromodomain inhibitors as anticancer therapeutics has transitioned from targeting bromodo main extraterminal domain (BET) proteins into targeting non-BET bromodomains. The two most relevant non-BET ... -
Sequential (3 + 2) cycloaddition and (5 + n) annulation for modular synthesis of dihydrobenzoxazines, tetrahydrobenzoxazepines and tetrahydrobenzoxazocines†
(2018-06)A two-step method for the (3 + 2) cycloaddition of azomethine ylides followed by a double SN2 substi tution-based (5 + n) annulation is introduced for the modular synthesis of dihydrobenzoxazine, tetra hydrobenzoxazepine ... -
Analysis of Effect of Inclined Magnetic Field on MHD Boundary Layer Flow over a Porous Exponentially Stretching Sheet Subject to Thermal Radiation
(2021-10-30)MHD flow has a wide range of industrial applications such as MHD propulsion for space exploration, cooling of nuclear reactors, electronic packages, microelectronic devices, and many more. Due to this, a study on the ... -
Efficacy of Mangrove (Rhizophora Mucronata) Roots Powder in Adsorption of Lead (II) Ions from Aqueous Solutions: Equilibrium and Kinetics Studies
(2016-08)The removal of Pb (II) ions by adsorption onto mangrove roots adsorbent was investigated in this present paper. The removal of lead ions from aqueous solutions was investigated in batch mode which involved the study of ...